Professor Anthony Shakeshaft’s principal research interests are in embedding the evaluation of interventions into the delivery of routine clinical health services and into the implementation of population-level interventions, with a particular interest in community-based approaches and Aboriginal and Torres Strait Islander health. His intervention trials have been conducted in partnership with a range of service providers, communities and academics to: examine the cost-effectiveness of alcohol brief interventions delivered in community-based counselling settings; the use of patient driven computers for screening and intervention in primary care (UK, Canada and Australia); improving the appropriateness of red blood cell transfusions in metropolitan hospitals; a national evaluation of pharmacotherapies for opioid dependence provided in drug and alcohol clinics; and increasing the provision of screening and brief intervention through Aboriginal Medical Services. He has also implemented a number of randomised controlled trials (RCTs) to evaluate: the cost-effectiveness of mailed personalised feedback to patients delivered through hospital emergency departments; the cost-effectiveness of mailed tailored feedback to GPs on their prescribing practices; and the cost-effectiveness of targeting high-risk weekends with community-based strategies aimed at reducing alcohol harms. Most recently he led the largest community-wide cluster RCT ever undertaken internationally aimed at reducing population level rates of risky drinking and alcohol-related harms – the Alcohol Action in Rural Communities (AARC) project.